Specific cloning of human DNA as yeast artificial chromosomes by transformation-associated recombination.

DNA molecules undergoing transformation into yeast are highly recombinogenic, even when diverged. We reasoned that transformation-associated recombination (TAR) could be employed to clone large DNAs containing repeat sequences, thereby eliminating the need for in vitro enzymatic reactions such as re...

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Main Authors: Larionov, V, Kouprina, N, Graves, J, Chen, X N, Korenberg, J R, Resnick, M A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1996
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC40264/
https://ncbi.nlm.nih.gov/pubmed/8552668
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