Changes in Gene Expression Associated with FTO Overexpression in Mice

Single nucleotide polymorphisms in the first intron of the fat-mass-and-obesity-related gene FTO are associated with increased body weight and adiposity. Increased expression of FTO is likely underlying this obesity phenotype, as mice with two additional copies of Fto (FTO-4 mice) exhibit increased...

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Bibliografiska uppgifter
Huvudupphovsmän: Merkestein, Myrte, McTaggart, James S., Lee, Sheena, Kramer, Holger B., McMurray, Fiona, Lafond, Mathilde, Boutens, Lily, Cox, Roger, Ashcroft, Frances M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026227/
https://ncbi.nlm.nih.gov/pubmed/24842286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097162
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