Phospholipase D1 and choline kinase-α are interactive targets in breast cancer

A consistent metabolic hallmark observed in multiple cancers is the increase of cellular phosphocholine (PC) and total choline-containing compounds (tCho), which is closely related to malignant transformation, invasion, and metastasis. Enzymes in choline phospholipid metabolism present attractive ta...

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Main Authors: Gadiya, Mayur, Mori, Noriko, Cao, Maria D, Mironchik, Yelena, Kakkad, Samata, Gribbestad, Ingrid S, Glunde, Kristine, Krishnamachary, Balaji, Bhujwalla, Zaver M
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026082/
https://ncbi.nlm.nih.gov/pubmed/24556997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28165
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