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Laying a solid foundation for Manhattan ‘Setting the functional basis for the post-GWAS era’
Genome-wide association studies (GWAS) have identified more than 8,900 genetic variants, mainly single nucleotide polymorphisms (SNPs), associated with hundreds of human traits and diseases, which define risk-associated loci. Variants that map to coding regions can affect protein sequence, translati...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026049/ https://ncbi.nlm.nih.gov/pubmed/24661571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2014.02.006 |
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