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Direct Role for Smooth Muscle Cell Mineralocorticoid Receptors in Vascular Remodeling: Novel Mechanisms and Clinical Implications

The mineralocorticoid receptor (MR) is a key regulator of blood pressure. MR-antagonist drugs are used to treat hypertension and heart failure, resulting in decreased mortality by mechanisms that are not completely understood. In addition to the kidney, MR is also expressed in the smooth muscle cell...

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Autori principali: Koenig, Jenny B., Jaffe, Iris Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026046/
https://ncbi.nlm.nih.gov/pubmed/24633842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11906-014-0427-y
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