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Mineralocorticoid-receptor signalling in vascular smooth muscle

Human data suggest that eplerenone and spironolactone lowers blood pressure by mechanisms independent of the distal tubule. Now, a novel inducible conditional knockout model of the mineralocorticoid receptor (MR) in vascular smooth muscle cells (VSMCs) brings out understanding further.

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Detalles Bibliográficos
Autores principales: Wu, Jing, Luft, Friedrich C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007112/
https://ncbi.nlm.nih.gov/pubmed/23439586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfs562
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