Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells

We show that expression of the microtubule depolymerizing kinesin KIF2C is induced by transformation of immortalized human bronchial epithelial cells by expression of K-Ras(G12V) and knockdown of p53. Further investigation demonstrates that this is due to the K-Ras/ERK1/2 MAPK pathway, as loss of p5...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zaganjor, Elma, Osborne, Jihan K., Weil, Lauren M., Diaz-Martinez, Laura A., Gonzales, Joshua X., Singel, Stina M., Larsen, Jill E., Girard, Luc, Minna, John D., Cobb, Melanie H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025984/
https://ncbi.nlm.nih.gov/pubmed/24240690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.486
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados