Dual-Target Virtual Screening by Pharmacophore Elucidation and Molecular Shape Filtering

[Image: see text] Dual-target inhibitors gained increased attention in the past years. A novel in silico approach was employed for the discovery of dual 5-lipoxygenase/soluble epoxide hydrolase inhibitors. The ligand-based approach uses excessive pharmacophore elucidation and pharmacophore alignment...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Moser, Daniel, Wisniewska, Joanna M., Hahn, Steffen, Achenbach, Janosch, Buscató, Estel·la, Klingler, Franca-Maria, Hofmann, Bettina, Steinhilber, Dieter, Proschak, Ewgenij
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2012
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025812/
https://ncbi.nlm.nih.gov/pubmed/24900445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200286e
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki