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Low Doses of Allyphenyline and Cyclomethyline, Effective against Morphine Dependence, Elicit an Antidepressant-like Effect
[Image: see text] This study demonstrated that cyclomethyline (2) and the corresponding enantiomers (R)-(−)-2 and (S)-(+)-2, displaying α(2C)-adrenoreceptor (AR) agonism/α(2A)-AR antagonism, similarly to allyphenyline (1) and its enantiomers, significantly decreased the naloxone-precipitated withdra...
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| Glavni autori: | , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American
Chemical Society
2012
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| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025786/ https://ncbi.nlm.nih.gov/pubmed/24900506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300064v |
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