Caricamento...
The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity
[Image: see text] Six focused rhodanine-based libraries, 60 compounds in total, were synthesized and evaluated as potential dynamin I GTPase inhibitors. Twenty-six were more potent than the lead compound with 13 returning IC(50) values ≤10 μM, making the Rhodadyn series among the most active dynamin...
Salvato in:
| Autori principali: | , , , , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical Society
2012
|
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025782/ https://ncbi.nlm.nih.gov/pubmed/24900478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200284s |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|