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Evaluation of [(11)C]N-Methyl Lansoprazole as a Radiopharmaceutical for PET Imaging of Tau Neurofibrillary Tangles

[Image: see text] [(11)C]N-Methyl lansoprazole ([(11)C]NML, 3) was synthesized and evaluated as a radiopharmaceutical for quantifying tau neurofibrillary tangle (NFT) burden using positron emission tomography (PET) imaging. [(11)C]NML was synthesized from commercially available lansoprazole in 4.6%...

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Detalhes bibliográficos
Main Authors: Shao, Xia, Carpenter, Garrett M., Desmond, Timothy J., Sherman, Phillip, Quesada, Carole A., Fawaz, Maria, Brooks, Allen F., Kilbourn, Michael R., Albin, Roger L., Frey, Kirk A., Scott, Peter J. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025667/
https://ncbi.nlm.nih.gov/pubmed/24900410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300216t
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