Longitudinal Requirement for CD4(+) T Cell Help for Adenovirus Vector–Elicited CD8(+) T Cell Responses

Despite the widespread use of replication-incompetent recombinant adenovirus (Ad) vectors as candidate vaccine platforms, the mechanism by which these vectors elicit CD8(+) T cell responses remains poorly understood. Our data demonstrate that induction and maintenance of CD8(+) T cell responses by A...

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Hlavní autoři: Provine, Nicholas M., Larocca, Rafael A., Penaloza-MacMaster, Pablo, Borducchi, Erica N., McNally, Anna, Parenteau, Lily R., Kaufman, David R., Barouch, Dan H.
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2014
Témata:
Immunotherapy and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025612/
https://ncbi.nlm.nih.gov/pubmed/24778441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302806
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