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Protective role of human insulin against the cytotoxicity associated with human mutant S20G islet amyloid polypeptide
AIMS/INTRODUCTION: Islet amyloid polypeptide (IAPP) is a main component of islet amyloid in type 2 diabetes and cosecreted from β‐cell with insulin. Clinical evidence from the patients with S20G mutation of the IAPP gene, as well as experimental evidence that insulin could inhibit amyloid formation...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley-Blackwell
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025108/ https://ncbi.nlm.nih.gov/pubmed/24843692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12069 |
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