Protective role of human insulin against the cytotoxicity associated with human mutant S20G islet amyloid polypeptide

AIMS/INTRODUCTION: Islet amyloid polypeptide (IAPP) is a main component of islet amyloid in type 2 diabetes and cosecreted from β‐cell with insulin. Clinical evidence from the patients with S20G mutation of the IAPP gene, as well as experimental evidence that insulin could inhibit amyloid formation...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Morita, Shuhei, Ueyama, Minoru, Sakagashira, Setsuya, Shimajiri, Yoshinori, Yamana, Akiko, Furuta, Machi, Sanke, Tokio
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley-Blackwell 2013
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025108/
https://ncbi.nlm.nih.gov/pubmed/24843692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12069
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky