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Neurosteroids promote phosphorylation and membrane insertion of extrasynaptic GABA(A) receptors

Neurosteroids are synthesized within the brain and act as endogenous anxiolytic, anticonvulsant, hypnotic, and sedative agents, actions that are principally mediated via their ability to potentiate phasic and tonic inhibitory neurotransmission mediated by γ-aminobutyric acid type A receptors (GABA(A...

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Main Authors: Abramian, Armen M., Comenencia-Ortiz, Eydith, Modgil, Amit, Vien, Thuy N., Nakamura, Yasuko, Moore, Yvonne E., Maguire, Jamie L., Terunuma, Miho, Davies, Paul A., Moss, Stephen J.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024867/
https://ncbi.nlm.nih.gov/pubmed/24778259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403285111
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