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Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABA(A) Receptors

The hypothalamic-pituitary-adrenal (HPA) axis, which mediates the body's response to stress, is largely under GABAergic control. Here we demonstrate that corticotropin-releasing hormone (CRH) neurons are modulated by the stress-derived neurosteroid, tetrahydrodeoxycorticosterone (THDOC), acting...

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Detalhes bibliográficos
Main Authors: Sarkar, Jhimly, Wakefield, Seth, MacKenzie, Georgina, Moss, Stephen J., Maguire, Jamie
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272883/
https://ncbi.nlm.nih.gov/pubmed/22171026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2560-11.2011
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