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The role of ovarian hormone-derived neurosteroids on the regulation of GABA(A) receptors in affective disorders

RATIONALE: Neuroactive derivatives of steroid hormones, neurosteroids, can act on GABA(A) receptors (GABA(A)Rs) to potentiate the effects of GABA on these receptors. Neurosteroids become elevated to physiologically relevant levels under conditions characterized by increased steroid hormones. There i...

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Main Authors: MacKenzie, Georgina, Maguire, Jamie
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090295/
https://ncbi.nlm.nih.gov/pubmed/24402140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3423-z
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