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The role of ovarian hormone-derived neurosteroids on the regulation of GABA(A) receptors in affective disorders

RATIONALE: Neuroactive derivatives of steroid hormones, neurosteroids, can act on GABA(A) receptors (GABA(A)Rs) to potentiate the effects of GABA on these receptors. Neurosteroids become elevated to physiologically relevant levels under conditions characterized by increased steroid hormones. There i...

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Detalhes bibliográficos
Main Authors: MacKenzie, Georgina, Maguire, Jamie
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090295/
https://ncbi.nlm.nih.gov/pubmed/24402140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3423-z
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