GFRα1 released by nerves enhances cancer cell perineural invasion through GDNF-RET signaling

The ability of cancer cells to invade along nerves is associated with aggressive disease and diminished patient survival rates. Perineural invasion (PNI) may be mediated by nerve secretion of glial cell line-derived neurotrophic factor (GDNF) attracting cancer cell migration through activation of ce...

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Bibliografske podrobnosti
Main Authors: He, Shuangba, Chen, Chun-Hao, Chernichenko, Natalya, He, Shizhi, Bakst, Richard L., Barajas, Fernando, Deborde, Sylvie, Allen, Peter J., Vakiani, Efsevia, Yu, Zhenkun, Wong, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024863/
https://ncbi.nlm.nih.gov/pubmed/24778213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402944111
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