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“Atypical”Regulation of Hedgehog-Dependent Cancers

Growing evidence indicates targeting PKCι may be effective in treating Hedgehog-dependent cancers. In this issue of Cancer Cell, Justilien and colleagues present the surprising finding that PKCι promotes Hedgehog ligand production and lung squamous cell carcinoma growth through SOX2, rather than the...

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Detalhes bibliográficos
Main Authors: Atwood, Scott X., Oro, Anthony E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024826/
https://ncbi.nlm.nih.gov/pubmed/24525228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.01.027
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