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Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy
Endosomal protein sorting controls the localization of many physiologically important proteins and is linked to several neurodegenerative diseases. VPS35 is a component of the retromer complex, which mediates endosome-to-Golgi retrieval of membrane proteins such as the cation-independent mannose 6-p...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4024763/ https://ncbi.nlm.nih.gov/pubmed/24819384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4828 |
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