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Role of intracellular calcium and NADPH oxidase NOX5-S in acid-induced DNA damage in Barrett's cells and Barrett's esophageal adenocarcinoma cells

Mechanisms whereby acid reflux may accelerate the progression from Barrett's esophagus (BE) to esophageal adenocarcinoma (EA) are not fully understood. Acid and reactive oxygen species (ROS) have been reported to cause DNA damage in Barrett's cells. We have previously shown that NADPH oxid...

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Detalhes bibliográficos
Main Authors: Li, Dan, Cao, Weibiao
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024726/
https://ncbi.nlm.nih.gov/pubmed/24699332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00321.2013
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