Role of Rac1 in regulation of NOX5-S function in Barrett's esophageal adenocarcinoma cells

We have shown that a novel NADPH oxidase isoform, NOX5-S, is the major isoform of NADPH oxidases in an esophageal adenocarcinoma (EA) cell line, FLO, and is overexpressed in Barrett's mucosa with high-grade dysplasia. NOX5-S is responsible for acid-induced reactive oxygen species production. In...

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Detalhes bibliográficos
Main Authors: Hong, Jie, Resnick, Murray, Behar, Jose, Wands, Jack, DeLellis, Ronald A., Cao, Weibiao
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Receptors and Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274187/
https://ncbi.nlm.nih.gov/pubmed/21525435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00027.2011
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