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Role of intracellular calcium and NADPH oxidase NOX5-S in acid-induced DNA damage in Barrett's cells and Barrett's esophageal adenocarcinoma cells

Mechanisms whereby acid reflux may accelerate the progression from Barrett's esophagus (BE) to esophageal adenocarcinoma (EA) are not fully understood. Acid and reactive oxygen species (ROS) have been reported to cause DNA damage in Barrett's cells. We have previously shown that NADPH oxid...

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Hlavní autoři: Li, Dan, Cao, Weibiao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024726/
https://ncbi.nlm.nih.gov/pubmed/24699332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00321.2013
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