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Structural dynamics of a single-stranded RNA–helix junction using NMR

Many regulatory RNAs contain long single strands (ssRNA) that adjoin secondary structural elements. Here, we use NMR spectroscopy to study the dynamic properties of a 12-nucleotide (nt) ssRNA tail derived from the prequeuosine riboswitch linked to the 3′ end of a 48-nt hairpin. Analysis of chemical...

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Bibliographic Details
Main Authors: Eichhorn, Catherine D., Al-Hashimi, Hashim M.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024633/
https://ncbi.nlm.nih.gov/pubmed/24742933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.043711.113
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