Biological effects of platelet-derived growth factor receptor α blockade in uterine cancer

PURPOSE: Platelet-derived growth factor receptor alpha (PDGFRα) expression is frequently observed in many kinds of cancer and is a candidate for therapeutic targeting. This preclinical study evaluated the biological significance of PDGFRα and PDGFRα blockade (using a fully humanized monoclonal antib...

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Bibliografiske detaljer
Main Authors: Roh, Ju-Won, Huang, Jie, Hu, Wei, Yang, XiaoYun, Jennings, Nicholas B., Sehgal, Vasudha, Sohn, Bo Hwa, Han, Hee Dong, Lee, Sun Joo, Thanapprapasr, Duangmani, Bottsford-Miller, Justin, Zand, Behrouz, Dalton, Heather J., Previs, Rebecca A., Davis, Ashley N., Matsuo, Koji, Lee, Ju-Seog, Ram, Prahlad, Coleman, Robert L., Sood, Anil K.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024372/
https://ncbi.nlm.nih.gov/pubmed/24634380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2507
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