Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer

PURPOSE: Cancer cells are highly dependent on folate metabolism, making them susceptible to drugs that inhibit folate receptor activities. Targeting overexpressed folate receptor alpha (FRα) in cancer cells offers a therapeutic opportunity. We investigated the functional mechanisms of MORAB-003 (far...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Clin Cancer Res
Главные авторы: Wen, Yunfei, Graybill, Whitney S., Previs, Rebecca A., Hu, Wei, Ivan, Cristina, Mangala, Lingegowda S., Zand, Behrouz, Nick, Alpa M., Jennings, Nicholas B., Dalton, Heather J., Sehgal, Vasudha, Ram, Prahlad, Lee, Ju-Seog, Vivas-Mejia, Pablo E., Coleman, Robert L., Sood, Anil K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297546/
https://ncbi.nlm.nih.gov/pubmed/25416196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1578
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы