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Yeast prions and human prion-like proteins: sequence features and prediction methods

Prions are self-propagating infectious protein isoforms. A growing number of prions have been identified in yeast, each resulting from the conversion of soluble proteins into an insoluble amyloid form. These yeast prions have served as a powerful model system for studying the causes and consequences...

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Autors principals: Cascarina, Sean M., Ross, Eric D.
Format: Artigo
Idioma:Inglês
Publicat: Springer Basel 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024371/
https://ncbi.nlm.nih.gov/pubmed/24390581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1543-6
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