Targeting Prolyl Endopeptidase with Valproic Acid as a Potential Modulator of Neutrophilic Inflammation

A novel neutrophil chemoattractant derived from collagen, proline-glycine-proline (PGP), has been recently characterized in chronic obstructive pulmonary disease (COPD). This peptide is derived via the proteolytic activity of matrix metalloproteases (MMP's)-8/9 and PE, enzymes produced by neutr...

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Détails bibliographiques
Auteurs principaux: Abdul Roda, Mojtaba, Sadik, Mariam, Gaggar, Amit, Hardison, Matthew T., Jablonsky, Michael J., Braber, Saskia, Blalock, James Edwin, Redegeld, Frank A., Folkerts, Gert, Jackson, Patricia L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023971/
https://ncbi.nlm.nih.gov/pubmed/24835793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097594
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