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Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) Analysis Uncovers Broad Changes in Chromatin Structure Resulting from Hexavalent Chromium Exposure

The ability of chromatin to switch back and forth from open euchromatin to closed heterochromatin is vital for transcriptional regulation and genomic stability, but its dynamic structure is subject to disruption by exposure to environmental agents such as hexavalent chromium. Cr(VI) exposure disrupt...

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Main Authors: Ovesen, Jerald L., Fan, Yunxia, Zhang, Xiang, Chen, Jing, Medvedovic, Mario, Xia, Ying, Puga, Alvaro
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023961/
https://ncbi.nlm.nih.gov/pubmed/24837440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097849
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