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Long-Term Exposure to Hexavalent Chromium Inhibits Expression of Tumor Suppressor Genes in cultured Cells and in Mice

We have used mouse hepatoma cells in culture to study acute, short-term high-dose effects of hexavalent chromium on gene regulation directed by the polycyclic aromatic hydrocarbon benzo[a]pyrene (BaP). We find that the mixture engages three major signaling pathways: (i) activation of detoxification...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fan, Yunxia, Ovesen, Jerald L., Puga, Alvaro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380135/
https://ncbi.nlm.nih.gov/pubmed/22613061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtemb.2012.04.009
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