Digital Expression Profiling Identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as Potential Predictive Biomarkers for Neo-Adjuvant Chemotherapy Response in Paediatric Osteosarcoma

Osteosarcoma is the most common malignancy of bone, and occurs most frequently in children and adolescents. Currently, the most reliable technique for determining a patients’ prognosis is measurement of histopathologic tumor necrosis following pre-operative neo-adjuvant chemotherapy. Unfavourable pr...

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Detalhes bibliográficos
Main Authors: Martin, Jeffrey W., Chilton-MacNeill, Susan, Koti, Madhuri, van Wijnen, Andre J., Squire, Jeremy A., Zielenska, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023931/
https://ncbi.nlm.nih.gov/pubmed/24835790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095843
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