Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy

BACKGROUND: Human osteosarcoma is the most common pediatric bone tumor. There is limited understanding of the molecular mechanisms underlying osteosarcoma oncogenesis, and a lack of good diagnostic as well as prognostic clinical markers for this disease. Recent discoveries have highlighted a potenti...

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Bibliografske podrobnosti
Main Authors: Sadikovic, Bekim, Thorner, Paul, Chilton-MacNeill, Susan, Martin, Jeff W, Cervigne, Nilva K, Squire, Jeremy, Zielenska, Maria
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875220/
https://ncbi.nlm.nih.gov/pubmed/20465837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-202
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