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SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel

Maintenance of a constant cell volume in response to extracellular or intracellular osmotic changes is critical for cellular homeostasis. Activation of a ubiquitous volume-regulated anion channel (VRAC) plays a key role in this process; however, its molecular identity in vertebrates remains unknown....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qiu, Zhaozhu, Dubin, Adrienne E., Mathur, Jayanti, Tu, Buu, Reddy, Kritika, Miraglia, Loren J., Reinhardt, Jürgen, Orth, Anthony P., Patapoutian, Ardem
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023864/
https://ncbi.nlm.nih.gov/pubmed/24725410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.024
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