Fucosylated Chondroitin Sulfate Inhibits Plasmodium falciparum Cytoadhesion and Merozoite Invasion

Sequestration of Plasmodium falciparum-infected erythrocytes (Pf-iEs) in the microvasculature of vital organs plays a key role in the pathogenesis of life-threatening malaria complications, such as cerebral malaria and malaria in pregnancy. This phenomenon is marked by the cytoadhesion of Pf-iEs to...

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Hauptverfasser: Bastos, Marcele F., Albrecht, Letusa, Kozlowski, Eliene O., Lopes, Stefanie C. P., Blanco, Yara C., Carlos, Bianca C., Castiñeiras, Catarina, Vicente, Cristina P., Werneck, Claudio C., Wunderlich, Gerhard, Ferreira, Marcelo U., Marinho, Claudio R. F., Mourão, Paulo A. S., Pavão, Mauro S. G., Costa, Fabio T. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023758/
https://ncbi.nlm.nih.gov/pubmed/24395239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00686-13
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