Fucosylated Chondroitin Sulfate Inhibits Plasmodium falciparum Cytoadhesion and Merozoite Invasion

Sequestration of Plasmodium falciparum-infected erythrocytes (Pf-iEs) in the microvasculature of vital organs plays a key role in the pathogenesis of life-threatening malaria complications, such as cerebral malaria and malaria in pregnancy. This phenomenon is marked by the cytoadhesion of Pf-iEs to...

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Hlavní autoři: Bastos, Marcele F., Albrecht, Letusa, Kozlowski, Eliene O., Lopes, Stefanie C. P., Blanco, Yara C., Carlos, Bianca C., Castiñeiras, Catarina, Vicente, Cristina P., Werneck, Claudio C., Wunderlich, Gerhard, Ferreira, Marcelo U., Marinho, Claudio R. F., Mourão, Paulo A. S., Pavão, Mauro S. G., Costa, Fabio T. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023758/
https://ncbi.nlm.nih.gov/pubmed/24395239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00686-13
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