Fucosylated Chondroitin Sulfate Inhibits Plasmodium falciparum Cytoadhesion and Merozoite Invasion

Sequestration of Plasmodium falciparum-infected erythrocytes (Pf-iEs) in the microvasculature of vital organs plays a key role in the pathogenesis of life-threatening malaria complications, such as cerebral malaria and malaria in pregnancy. This phenomenon is marked by the cytoadhesion of Pf-iEs to...

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Autors principals: Bastos, Marcele F., Albrecht, Letusa, Kozlowski, Eliene O., Lopes, Stefanie C. P., Blanco, Yara C., Carlos, Bianca C., Castiñeiras, Catarina, Vicente, Cristina P., Werneck, Claudio C., Wunderlich, Gerhard, Ferreira, Marcelo U., Marinho, Claudio R. F., Mourão, Paulo A. S., Pavão, Mauro S. G., Costa, Fabio T. M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023758/
https://ncbi.nlm.nih.gov/pubmed/24395239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00686-13
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