A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system

BACKGROUND: Copper is essential for the survival of aerobic organisms. If copper is not properly regulated in the body however, it can be extremely cytotoxic and genetic mutations that compromise copper homeostasis result in severe clinical phenotypes. Understanding how cells maintain optimal copper...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schlecht, Ulrich, Suresh, Sundari, Xu, Weihong, Aparicio, Ana Maria, Chu, Angela, Proctor, Michael J, Davis, Ronald W, Scharfe, Curt, St Onge, Robert P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023593/
https://ncbi.nlm.nih.gov/pubmed/24708151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-263
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