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A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system
BACKGROUND: Copper is essential for the survival of aerobic organisms. If copper is not properly regulated in the body however, it can be extremely cytotoxic and genetic mutations that compromise copper homeostasis result in severe clinical phenotypes. Understanding how cells maintain optimal copper...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023593/ https://ncbi.nlm.nih.gov/pubmed/24708151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-263 |
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