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Data‐driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

The extracellular signal‐regulated kinase (ERK) signaling pathway controls cell proliferation and differentiation in metazoans. Two hallmarks of its dynamics are adaptation of ERK phosphorylation, which has been linked to negative feedback, and nucleocytoplasmic shuttling, which allows active ERK to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ahmed, Shoeb, Grant, Kyle G, Edwards, Laura E, Rahman, Anisur, Cirit, Murat, Goshe, Michael B, Haugh, Jason M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: European Molecular Biology Organization 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023404/
https://ncbi.nlm.nih.gov/pubmed/24489118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/msb.134708
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