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Genome-wide analysis of parent-of-origin effects in non-syndromic orofacial clefts
Parent-of-origin (PofO) effects, such as imprinting are a phenomenon where the effect of variants depends on parental origin. Conventional association studies assume that phenotypic effects are independent of parental origin, and are thus severely underpowered to detect such non-Mendelian effects. R...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023210/ https://ncbi.nlm.nih.gov/pubmed/24169523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.235 |
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