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Folic Acid Supplementation Use and the MTHFR C677T Polymorphism in Orofacial Clefts Etiology: An Individual Participant Data Pooled-Analysis

BACKGROUND: This study examines gene-environment interaction (GEI) between the MTHFR C667T polymorphism and folic acid in the etiology of orofacial clefts (OFC). We used a pooled-analyticapproach on four studies that used similar methods. METHODS: We used logistic regression to analyse the pooled sa...

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Detalhes bibliográficos
Main Authors: Butali, Azeez, Little, Julian, Chevrier, Cécile, Cordier, Sylvian, Steegers-Theunissen, Regine, Jugessur, Astanand, Oladugba, Bola, Mossey, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745533/
https://ncbi.nlm.nih.gov/pubmed/23670871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23133
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