Hepatocyte Growth Factor (Hgf) Stimulates Low Density Lipoprotein Receptor-related Protein (Lrp) 5/6 Phosphorylation and Promotes Canonical Wnt Signaling

While Wnt and Hgf signaling pathways are known to regulate epithelial cell responses during injury and repair, whether they exhibit functional cross-talk is not well defined. Canonical Wnt signaling is initiated by the phosphorylation of the Lrp5/6 co-receptors. In the current study we demonstrate t...

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Bibliografiske detaljer
Main Authors: Koraishy, Farrukh M., Silva, Cynthia, Mason, Sherene, Wu, Dianqing, Cantley, Lloyd G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022900/
https://ncbi.nlm.nih.gov/pubmed/24692544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563213
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