Pro(178) and Pro(183) of Selenoprotein S Are Essential Residues for Interaction with p97(VCP) during Endoplasmic Reticulum-associated Degradation

During endoplasmic reticulum (ER)-associated degradation, p97(VCP) is recruited to the ER membrane through interactions with transmembrane proteins, such as selenoprotein S (SelS), selenoprotein K (SelK), hrd1, and gp78. SelS has a single-spanning transmembrane domain and protects cells from ER stre...

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Autores principales: Lee, Jea Hwang, Kwon, Joon Hyun, Jeon, Yeong Ha, Ko, Kwan Young, Lee, Seung-Rock, Kim, Ick Young
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022850/
https://ncbi.nlm.nih.gov/pubmed/24700463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534529
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