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Oral Tolerance to Cancer Can Be Abrogated by T Regulatory Cell Inhibition

Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage. We investigated the utilisation of regulatory T cell (Treg...

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Detalhes bibliográficos
Main Authors: Whelan, Maria C., Casey, Garrett, Larkin, John O., Guinn, Barbara-ann, O'Sullivan, Gerald C., Tangney, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022586/
https://ncbi.nlm.nih.gov/pubmed/24832130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097602
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