Prostate Stem Cell Antigen DNA Vaccination Breaks Tolerance to Self-antigen and Inhibits Prostate Cancer Growth

Prostate stem cell antigen (PSCA) is a cell surface antigen expressed in normal human prostate and over expressed in prostate cancer. Elevated levels of PSCA protein in prostate cancer correlate with increased tumor stage/grade, with androgen independence and have higher expression in bone metastase...

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Bibliographic Details
Main Authors: Ahmad, Sarfraz, Casey, Garrett, Sweeney, Paul, Tangney, Mark, O'Sullivan, Gerald C
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835175/
https://ncbi.nlm.nih.gov/pubmed/19337234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.66
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