Up-regulation of heme oxygenase-1 after infarct initiation reduces mortality, infarct size and left ventricular remodeling: experimental evidence and proof of concept

BACKGROUND: Up-regulation of HO-1 by genetic manipulation or pharmacological pre-treatment has been reported to provide benefits in several animal models of myocardial infarction (MI). However, its efficacy following MI initiation (as in clinical reality) remains to be tested. Therefore, this study...

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Bibliografische gegevens
Hoofdauteurs: Kusmic, Claudia, Barsanti, Cristina, Matteucci, Marco, Vesentini, Nicoletta, Pelosi, Gualtiero, Abraham, Nader G, L’Abbate, Antonio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022338/
https://ncbi.nlm.nih.gov/pubmed/24708733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-89
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