Up-regulation of heme oxygenase-1 after infarct initiation reduces mortality, infarct size and left ventricular remodeling: experimental evidence and proof of concept

BACKGROUND: Up-regulation of HO-1 by genetic manipulation or pharmacological pre-treatment has been reported to provide benefits in several animal models of myocardial infarction (MI). However, its efficacy following MI initiation (as in clinical reality) remains to be tested. Therefore, this study...

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Detalhes bibliográficos
Main Authors: Kusmic, Claudia, Barsanti, Cristina, Matteucci, Marco, Vesentini, Nicoletta, Pelosi, Gualtiero, Abraham, Nader G, L’Abbate, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022338/
https://ncbi.nlm.nih.gov/pubmed/24708733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-89
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