Heme Oxygenase-1 Induction Remodels Adipose Tissue and Improves Insulin Sensitivity in Obesity-Induced Diabetic Rats

Obesity-associated inflammation causes insulin resistance. Obese adipose tissue displays hypertrophied adipocytes and increased expression of the cannabinoid-1 receptor. Cobalt protoporphyrin (CoPP) increases heme oxygenase-1 (HO-1) activity, increasing adiponectin and reducing inflammatory cytokine...

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Detalhes bibliográficos
Main Authors: Nicolai, Angelique, Li, Ming, Kim, Dong Hyun, Peterson, Stephen J., Vanella, Luca, Positano, Vincenzo, Gastaldelli, Amalia, Rezzani, Rita, Rodella, Luigi F., Drummond, George, Kusmic, Claudia, L’Abbate, Antonio, Kappas, Attallah, Abraham, Nader G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745551/
https://ncbi.nlm.nih.gov/pubmed/19171794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.124701
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