Accumulation of Misfolded SOD1 in Dorsal Root Ganglion Degenerating Proprioceptive Sensory Neurons of Transgenic Mice with Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is an adult-onset progressive neurodegenerative disease affecting upper and lower motoneurons (MNs). Although the motor phenotype is a hallmark for ALS, there is increasing evidence that systems other than the efferent MN system can be involved. Mutations of super...

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Hlavní autoři: Sábado, Javier, Casanovas, Anna, Tarabal, Olga, Hereu, Marta, Piedrafita, Lídia, Calderó, Jordi, Esquerda, Josep E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022303/
https://ncbi.nlm.nih.gov/pubmed/24877142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/852163
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