A novel anti-CD19 monoclonal antibody (GBR 401) with high killing activity against B cell malignancies

BACKGROUND: CD19 is a B cell lineage specific surface receptor whose broad expression, from pro-B cells to early plasma cells, makes it an attractive target for the immunotherapy of B cell malignancies. In this study we present the generation of a novel humanized anti-CD19 monoclonal antibody (mAb),...

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Detalhes bibliográficos
Main Authors: Breton, Caroline S, Nahimana, Aimable, Aubry, Dominique, Macoin, Julie, Moretti, Pierre, Bertschinger, Martin, Hou, Samuel, Duchosal, Michel A, Back, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021825/
https://ncbi.nlm.nih.gov/pubmed/24731302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-7-33
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