Multipoint targeting of the PI3K/mTOR pathway in mesothelioma

BACKGROUND: Mesothelioma is a notoriously chemotherapy-resistant neoplasm, as is evident in the dismal overall survival for patients with those of asbestos-associated disease. We previously demonstrated co-activation of multiple receptor tyrosine kinases (RTKs), including epidermal growth factor rec...

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Bibliografiske detaljer
Main Authors: Zhou, S, Liu, L, Li, H, Eilers, G, Kuang, Y, Shi, S, Yan, Z, Li, X, Corson, J M, Meng, F, Zhou, H, Sheng, Q, Fletcher, J A, Ou, W-B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021537/
https://ncbi.nlm.nih.gov/pubmed/24762959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.220
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